Thermo Fisher Scientific RNF41 Polyclonal Antibody
RNF41 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot에 최적화되어 있습니다. 인간, 생쥐, 랫트 시료에 반응하며, 고순도 친화 크로마토그래피 정제 및 안정적인 PBS/glycerol 버퍼로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human RNF41 (aa 153–177, length 317) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2692035 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
The RING-type zinc finger motif is present in many viral and eukaryotic proteins and consists of a conserved cysteine-rich domain capable of binding two zinc atoms.
Proteins containing this domain are generally involved in the ubiquitination pathway for protein degradation.
Nrdp1, also known as RNF41 (RING finger protein 41), SBBI03, or FLRF, is a 317 amino acid protein featuring one RING-type zinc finger and one SIAH-type zinc finger.
It is expressed in testis, ovary, and prostate, functioning as an E3 ubiquitin-protein ligase that transfers ubiquitin from E2 conjugating enzymes to substrates targeted for degradation.
Specifically, Nrdp1 interacts with ErbB-3 and UBPY, leading to their proteasomal degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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