Thermo Fisher Scientific Phospho-TERT (Ser227) Polyclonal Antibody
인간 TERT 단백질의 Ser227 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, ICC/IF, Flow Cytometry, peptide-ELISA에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
| Flow Cytometry (Flow) | - | View 1 publication |
| Peptide-ELISA (pep-ELISA) | 1:1,000 | - |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human Telomerase around the phosphorylation site of Ser227 (G-G-SP-A-S) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555410 |
Target Information
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity and an RNA component serving as a template for the telomere repeat. Telomerase expression plays a key role in cellular senescence and oncogenesis, being normally repressed in postnatal somatic cells. Studies suggest telomerase may also participate in chromosomal repair. Multiple alternatively spliced variants of TERT have been identified, though some full-length sequences remain undetermined.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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