Thermo Fisher Scientific UL13_HHV11 Polyclonal Antibody
인간 UL13_HHV11 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. 합성 펩타이드로 면역화되어 높은 특이성을 가지며, 액상 형태로 제공됩니다. PBS/glycerol 완충액에 보관하며 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human UL13_HHV11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691522 |
Target Information
UL13 is a multifunctional serine/threonine kinase involved in multiple processes such as viral particle egress from the nucleus, modulation of the actin cytoskeleton, and regulation of viral and cellular gene expression. It regulates nuclear localization of viral envelopment factors UL34 and UL31 by phosphorylating the US3 kinase, contributing to nuclear egress. UL13 disrupts host nuclear lamins (LMNA, LMNB1) and phosphorylates viral Fc receptor glycoproteins E (gE) and I (gI), affecting subcellular localization of gE. It also participates in transcriptional regulation of cellular and viral mRNAs via phosphorylation of ICP22, and other substrates such as UL41, UL49, and host EF1D.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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