Thermo Fisher Scientific RAB11FIP1 Polyclonal Antibody
Human RAB11FIP1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS 및 글리세롤 버퍼에 보존됩니다. 세포 내 Rab GTPase 관련 막 수송 연구에 활용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RAB11FIP1. Recombinant protein control fragment (Product #RP-93847). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646206 |
Product Specific Information
Immunogen sequence:
TGSAKHRLHP VKPMNAMATK VANCSLGTAT IISENLNNEV MMKKYSPSDP AFAYAQLTHD ELIQLVLKQK ETISKKEFQV R
Antigen sequence identity:
- Mouse: 84%
- Rat: 84%
Target Information
Rab11-FIP1 (Rab 11 family-interacting protein 1), also known as Rab-coupling protein (RCP), is a 1283 amino acid Rab 11 effector protein.
Rab11-FIP1 interacts with Rab GTPases and is involved in endosomal recycling and membrane trafficking along the phagocytic pathway.
Localized to the recycling endosome, cytoplasmic membrane, and phagosome membranes, it is expressed as five isoforms produced by alternative splicing.
Isoform two is the most highly expressed and found in brain, lung, testis, small intestine, spleen, and heart.
Isoform two forms homooligomers and interacts with Rab 4A, Rab 11A, Rab 11B, and Rab 25.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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