Thermo Scientific™

TheraPure™ 2`-Fluoro-Ac-C Phosphoramidite, 20-400 finish bottle

2-Fluoro-Ac-C CEP is a phosphoramidite containing 5 DMT and the nucleoside cytidine (C) with 2`-Fluoro protection, for use in oligonucleotide자세히 알아보기

2-Fluoro-Ac-C CEP is a phosphoramidite containing 5 DMT and the nucleoside cytidine (C) with 2-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2-OH), the 2-F modification has been proven useful in antisense, siRNA, and aptamer applications. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

사양

31P NMR 순도≥98%

형식Amber bottle (20-400 finish neck style)

용도(장비)Expedite Synthesizers

설명Base: C
Base Protection: Ac

분자량789.8 g/mol

제품 유형2in-Fluoro-Ac-C CEP

뉴클레오시드 유형Cytidine (C)

시약 특징2in-Fluoro modified, Fast deprotection

배송 조건Room Temperature

순도>98% (HPLC)

수량0.25 g

시약 유형Phosphoramidite

등급TheraPure™

핵산 유형RNA

제품라인TheraPure™

용도(애플리케이션)Oligonucleotide synthesis

형태Powder

화학물질 이름 또는 재질5-O-(4,4-Dimethoxytrityl)-N4-acetyl-2-fluorocytidine-3-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

분자식C41H49N5FO8P

CAS159414-99-0

Unit Size0.25 g