Thermo Fisher Scientific Angiogenin Polyclonal Antibody
인간 Angiogenin에 특이적인 Rabbit Polyclonal Antibody로 다양한 응용(WB, IHC, ICC/IF)에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 감도를 제공. 연구용으로 신생혈관 형성과 종양 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 5–30 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–30 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.5–3 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Angiogenin (amino acid range 25–147 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903448 |
Target Information
Angiogenin (ANG or ANG I) is critical for neovascularization and new blood vessel formation. It is similar to pancreatic ribonuclease A and acts as a tRNA-specific ribonuclease that inhibits protein synthesis by hydrolyzing cellular tRNAs. ANG interacts with endothelial cell-surface actin, affecting the cytoskeleton and may play a role in solid tumor development. Its antagonists can inhibit tumor growth. Mutations in ANG are associated with amyotrophic lateral sclerosis type 9 (ALS9), linking ANG to both ALS and Parkinson’s disease.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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