Thermo Fisher Scientific BCAR1 Monoclonal Antibody (OTI3A11), TrueMAB
BCAR1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI3A11). Western blot, IHC, ICC/IF, Flow cytometry에 적합. Human, Mouse, Rat, Dog 반응성. Affinity chromatography로 정제된 Liquid 형태로, PBS/BSA/glycerol buffer에 보존됨.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A11 |
| Immunogen | Full length human recombinant protein of human BCAR1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.66 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signaling via v-Crk and v-Src oncoproteins. It contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich region. p130Cas is involved in various biological processes including cell adhesion, migration, growth factor stimulation, cytokine receptor engagement, and bacterial infection. Its physiological roles include cardiovascular development, actin filament assembly, and Src-induced cell transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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