Thermo Fisher Scientific RPS6KA2 Monoclonal Antibody (OTI2H10), TrueMAB

Thermo Fisher Scientific RPS6KA2 Monoclonal Antibody (OTI2H10), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

RPS6KA2 (RSK3) serine/threonine kinase is a member of the ribosomal S6 kinase (RSK) family. It acts as a signal-transducing intermediate in cellular responses to various growth factors. It is expressed in many tissues, with higher levels in lung and skeletal muscle.
The p90 ribosomal S6 kinases (RSK1–4) are downstream members of the ERK/MAPK cascade. Loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, characterized by mental retardation and growth deficits, possibly affecting G-protein coupled signaling regulation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.