Thermo Fisher Scientific BCLAF1 Polyclonal Antibody
Thermo Fisher Scientific의 BCLAF1 Polyclonal Antibody는 Rat 반응성을 가지며 Western blot에 적합합니다. Rabbit IgG 포맷의 액상 항체로, 합성 펩타이드 면역원 기반입니다. 0.5 mg/mL 농도로 제공되며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1.0 µg/mL
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Published Species | Mouse, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of rat BCLAF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689003 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%.
Target Information
BCLAF1 is an intracellular, death-promoting transcriptional repressor of survival genes that interacts with several members of the BCL2 family of proteins. It shows homology to the basic leucine zipper (bZIP) and MYB DNA binding domains.
In apoptotic cells, BCLAF1 localizes to dot-like structures throughout the nucleus and redistributes near the nuclear envelope. Overexpression induces apoptosis, which can be suppressed by co-expression of BCL2 proteins.
Also known as BTF, it triggers a proapoptotic signal potentially helpful in overcoming resistance to STI571. BCLAF1 is predominantly expressed in skeletal muscles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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