Thermo Fisher Scientific ZC3HAV1 Polyclonal Antibody
Thermo Fisher Scientific의 ZC3HAV1 Polyclonal Antibody는 인간 단백질에 반응하는 Rabbit IgG 기반 항체로, WB, IHC, ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고농도 액상 형태로 제공되어 안정적인 연구용 분석에 활용 가능합니다.
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Thermo Fisher Scientific ZC3HAV1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:5,000–1:20,000 | View 4 publications |
| Immunohistochemistry (IHC) | – | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | – |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | View 2 publications |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 401–721 of Human ZC3HAV1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.35 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7) with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549123 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
Target Information
ZC3HAV1 (zinc finger antiviral protein) is a CCCH-type zinc finger protein that induces innate immunity against retroviral infections by preventing viral RNA accumulation in the cytoplasm. It recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 localizes in the cytoplasm at steady state but shuttles between the nucleus and cytoplasm in an XPO1-dependent manner. ZAP is a direct target gene of IRF3 in antiviral responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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