Thermo Fisher Scientific mGluR2/mGluR3 Polyclonal Antibody
Rat mGluR2/mGluR3 인식 Rabbit Polyclonal Antibody로 WB, IHC, ICC/IF에 사용 가능. mGluR2와 mGluR3 사이 100% 보존된 서열에 반응하며, 인간 및 마우스에도 예측 반응. Affinity chromatography로 정제된 액상 형태로, 1 mg/mL 농도.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (IHC) | 1:250 |
| Immunocytochemistry (ICC/IF) | 1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Rat mGluR2/3 residues 860–872 (NGREVVDSTTSSL) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1958342 |
Product Specific Information
PA1-30151 detects mGluR2 and mGluR3 from rat samples.
The sequence is 100% conserved between mGluR2 and mGluR3.
Predicted to react with human and mouse.
Target Information
The mGluR proteins (metabotropic Glutamate Receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic Glutamate Receptors).
The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways.
- mGluR1 and mGluR5 activate a phosphatidylinositol-calcium second messenger system and generate a calcium-activated chloride current.
- The remaining mGluR subtypes inhibit adenylate cyclase activity.
mGluR-3, which may interact with GRASP, acts as a receptor for glutamate.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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