Thermo Fisher Scientific 4EBP1 Polyclonal Antibody
4EBP1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC 및 IHC(Paraffin) 응용에 적합합니다. 인간과 마우스에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 4°C에서 보관합니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 75 and the C-terminus (residue 118) of human eukaryotic translation initiation factor 4E binding protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 50 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Rabbit, Pig, Orangutan, Monkey, Gorilla, Chimpanzee, Thirteen-lined ground squirrel, Chinese hamster, and Crab-eating macaque.
Target Information
This gene encodes one member of a family of translation repressor proteins.
The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs.
Interaction of this protein with eIF4E inhibits complex assembly and represses translation.
This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지: IHC-00133_4EBP1_Q13541-1_Rabbit.svg, IHC-00133_4EBP1_Q13541-1_Rabbit_PDP.jpeg)
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