Thermo Fisher Scientific RNF17 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 900-1200 of human RNF17 (NP_112567.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RNF17,uniProtId:Q9BXT8-3,ncbiNodeId:9606,antigenRange:900-1200,antigenLength:1623,antigenImageFileName:PA5-110307_RNF17_Q9BXT8-3_Rabbit.svg,antigenImageFileNamePDP:PA5-110307_RNF17_Q9BXT8-3_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.82 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855718

Product Specific Information

Immunogen sequence: VSAKSLPNEN FQSLYNKELP VHICNVISPE KIYVQWLLTE NLLNSLEEKM IAAYENSKWE PVKWENDMHC AVKIQDKNQW RRGQIIRMVT DTLVEVLLYD VGVELVVNVD CLRKLEENLK TMGRLSLECS LVDIRPAGGS DKWTATACDC LSLYLTGAVA TIILQVDSEE NNTTWPLPVK IFCRDEKGER VDVSKYLIKK GLALRERRIN NLDNSHSLSE KSLEVPLEQE DSVVTNCIKT NFDPDKKTAD IISEQKVSEF QEKILEPRTT RGYKPPAIPN MNVFEATVSC VGDDGTIFVV P

Target Information

RNF17 also termed as ring finger protein 17 is a 1623 amino acid protein, which contains 1 ring type zinc finger and 4 tudor domains. RNF17 is specifically expressed in testis. The RING finger motif presents in many ubiquitin E3 ligases. RNF17 interacts with all four members of the Mad family (Mad1, Mxi1, Mad3 and Mad4), which are basic-helix-loop-helix-leucine zipper transcription factors of the Myc oncoprotein network. RNF17 is component of the tectonic-like complex, which is required for ciliogenesis and sonic hedgehog/SHH signaling. RNF17 is able to form dimers or polymers both in vitro and in vivo, indicating that it may play a role in the assembly of RNF17 granules. RNF17 encodes a novel key regulator of spermiogenesis.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.