Thermo Fisher Scientific TOB2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human TOB2 protein. Validated for WB, IHC(P), and ELISA applications. Suitable for research in cell cycle regulation and transcriptional repression. Supplied in liquid form with PBS/glycerol buffer and stored at -20°C.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–70 of human TOB2 (NP_057356.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.11 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855915 |
Product Specific Information
Immunogen sequence:
MQLEIKVALN FIISYLYNKL PRRRADLFGE ELERLLKKKY EGHWYPEKPL KGSGFRCVHI GEMVDPVVEL
Target Information
TOB2 is a 344-amino-acid member of the Tob/BTG1 anti-proliferative protein family, characterized by its N-terminal BTG/Tob homology domain. This protein inhibits cell cycle progression from G0/G1 to S phase and regulates transcription through interactions with Caf1, a component of the CCR4 complex. TOB2 is implicated in processes such as spermatogenesis, embryonic patterning, osteogenesis, T-cell activation, and learning and memory. It acts primarily as a transcriptional repressor and is ubiquitously expressed in most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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