Thermo Fisher Scientific SNRNP200 Polyclonal Antibody
SNRNP200 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, IP 등 다양한 응용에 사용 가능. Human SNRNP200(aa 400–450) 항원으로 제작. 1 mg/mL 농도의 액상 형태로 4°C 보관. 연구용으로만 사용.
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- A303454Ax (2개 옵션)
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Applications and Tested Dilutions
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 400 and 450 of Human Small Nuclear Ribonucleoprotein 200kDa (SNRNP200, UniProt ID: O75643-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from the date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Rat
Target Information
Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from transcribed pre-mRNA. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5, and U6, along with approximately 80 conserved proteins.
U5 snRNP contains nine specific proteins, and this gene encodes one of them. The encoded protein belongs to the DEXH-box family of putative RNA helicases and acts as a core component of U4/U6-U5 snRNPs, catalyzing ATP-dependent unwinding of U4/U6 RNA duplexes.
Mutations in this gene are associated with autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been identified, though their full-length nature remains uncharacterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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