Thermo Fisher Scientific Pol kappa Polyclonal Antibody
Rabbit polyclonal antibody against human DNA polymerase kappa (POLK). Validated for WB and IP applications. Antigen affinity purified, supplied as liquid form at 0.2 mg/mL. Recommended storage at 4°C for research use only.
- 카탈로그번호
- A301975A
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Pol kappa Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 675 and 725 of Human DNA polymerase kappa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although various repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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