Thermo Fisher Scientific PLS3 Polyclonal Antibody
인간 PLS3 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 적합합니다. 0.5 mg/mL 농도의 액상 제품이며, PBS 및 sucrose buffer에 보관됩니다. PKC-delta 관련 apoptosis 연구에 활용됩니다.
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Applications
- Western Blot (WB): Tested dilution 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human PLS3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609437 |
Product Specific Information
- Peptide sequence: RRYTLNVLED LGDGQKANDD IIVNWVNRTL SEAGKSTSIQ SFKDKTISSS
- Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 77%
Target Information
Phospholipid scramblases (PLS) translocate phospholipids bidirectionally between inner and outer leaflets of the plasma membrane and are implicated in apoptosis. Members of this family, PLS1 and PLS3, are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in HEK293 cells enhances apoptosis induced by UV irradiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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