Thermo Fisher Scientific Human BICD1 Synthetic Peptide
인간 BICD1 단백질의 카복시 말단 17개 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20555와 함께 블로킹 펩타이드로 사용 가능. 세포 내 수송 및 골지-ER 경로 연구에 활용. 연구용으로만 사용.
- 카탈로그번호
- PEP0675
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human BICD1 Synthetic Peptide
Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the carboxy terminus of human BICD1.
PEP-0675 can be used as a blocking peptide with polyclonal antibody PA5-20555.
Target Information
BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis.
BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport.
BICD1 also interacts with Rab6B, a Rab6 isoform expressed primarily in the brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating BICD1 involvement in Rab6B regulation of retrograde cargo transport in neuronal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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