Thermo Fisher Scientific RNF41 Polyclonal Antibody
RNF41 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능하며 Human에 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, 단기 4°C 보관 및 장기 -20°C 보관 권장.
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Thermo Fisher Scientific RNF41 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 47–232 of Human RNF41 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.99 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547836 |
Product Specific Information
- Recommended positive controls: 293T, A431
- Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (91%), Xenopus laevis (95%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The RING-type zinc finger motif is a conserved cysteine-rich domain capable of binding two zinc atoms, found in various viral and eukaryotic proteins. These proteins are typically involved in the ubiquitination pathway of protein degradation.
Nrdp1, also known as RNF41 (RING finger protein 41), SBBI03, or FLRF, is a 317 amino acid protein containing one RING-type zinc finger and one SIAH-type zinc finger. Expressed in testis, ovary, and prostate, Nrdp1 acts as an E3 ubiquitin-protein ligase, transferring ubiquitin from an E2 enzyme to target substrates for degradation. It interacts with ErbB-3 and UBPY, targeting them for proteasomal degradation.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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