Thermo Fisher Scientific LMTK3 Polyclonal Antibody

Applications and Tested Dilution

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Target Information

Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804).
Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.