Thermo Fisher Scientific UBE2D2 Monoclonal Antibody (OTI1H4), TrueMAB
UBE2D2 단백질을 인식하는 Mouse IgG2b 단일클론 항체로 Western blot에 적합. 인간 시료 반응성이 있으며, 고순도의 액상 형태(1 mg/mL)로 제공. 단백질 유비퀴틴화 연구 및 p53 관련 단백질 분해 경로 분석에 활용 가능.
- 카탈로그번호
- TA806504
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H4 |
| Immunogen | Full-length human recombinant protein of UBE2D2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The modification of proteins with ubiquitin is an essential cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves three main classes of enzymes:
- E1: Ubiquitin-activating enzymes
- E2: Ubiquitin-conjugating enzymes
- E3: Ubiquitin-protein ligases
UBE2D2 encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme participates in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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