Thermo Fisher Scientific RXRG Polyclonal Antibody
RXRG 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot에 최적화되어 있으며, 다양한 종에 반응 예측. 합성 펩타이드 면역원 기반으로 제작, 0.5 mg/mL 농도의 액상 형태로 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PA518311
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (RQRSRERAESEAEC) corresponding to the internal amino acids of RXRG (aa 213–227). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10981574 |
Product Specific Information
- Predicted to react with bovine, canine, mouse, porcine, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
Retinoic Acid (RA), the active metabolite of vitamin A, regulates the transition of proliferating precursor cells (e.g., carcinoma and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005).
The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors.
RAs may play a therapeutic role in cervical cancer (Abu et al., 2005) and are known to be key regulators in neuronal development. Increasing evidence suggests that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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