Thermo Fisher Scientific PODXL2 Monoclonal Antibody (OTI10D8), TrueMAB
인간 PODXL2 단백질(aa 366-486)에 특이적인 Mouse IgG1 단클론 항체. Western blot에 1:2,000 희석으로 검증됨. 무보존제, 동결건조 형태로 제공되며, 재구성 및 결합 실험에 적합. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10D8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 366–486 of human PODXL2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Podocalyxin-like protein 2 (PODXL2) is a CD34 family member expressed by podocytes, vascular endothelium, mesothelium, and certain hematopoietic progenitors. It is a major sialoprotein in the glycocalyx of glomerular podocytes.
Although its role in leukemic blasts is unclear, PODXL2 is considered a candidate gene related to tumor aggressiveness in prostate cancer. It complements CD34 as a useful surface marker for hemangioblasts, the common precursors of hematopoietic and endothelial cells.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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