Thermo Fisher Scientific Phospho-GABBR2 (Ser783) Polyclonal Antibody
Phospho-GABBR2 (Ser783) 항체로 Western blot, IHC, ICC/IF에 사용 가능. Mouse와 Rat에 반응하며 Rabbit Polyclonal 형태. Affinity chromatography로 정제, -20°C 보관. 신경전달 억제 관련 GABAB R2 단백질 연구용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser783 of rat GABBR2 conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2263147 |
Product Specific Information
This antibody is predicted to react with bovine, canine, chicken, human, mouse, and non-human primate based on 100% sequence homology.
In Western blot, PA1-4705 detects the ~102 kDa GABAB R2 protein phosphorylated at Ser783.
Target Information
The multi-pass membrane protein GABBR2 belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily.
GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, regulating neurotransmitter release and ion channel and adenylyl cyclase activity.
This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective alone.
Allelic variants of this gene have been associated with nicotine dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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