Thermo Fisher Scientific SLC37A2 Polyclonal Antibody
Human SLC37A2 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:20–1:50 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 40% 글리세롤 용액에 보관. 비만 관련 대식세포 연구 등 SLC37A2 발현 분석에 적합.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SLC37A2. Recombinant protein control fragment (Product # RP-91270) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647488 |
Product Specific Information
Immunogen sequence:
RKPISIVKSR LHQNCSEQIK PINDTHSLND TMWCSWAPFD KDNYKE
Antigen sequence identity:
- Mouse: 83%
- Rat: 80%
Target Information
The Slc37 gene family consists of four members with 10–12 predicted transmembrane domains, belonging to the sugar-phosphate transporter superfamily.
Slc37A2 is a macrophage-specific gene selectively expressed in obese white adipose tissue. It is also expressed in spleen, thymus, and cell lines such as RAW264.7 and THP-1.
In ob/ob mice, Slc37A2 mRNA expression is approximately nine-fold higher in abdominal epididymal fat compared to wild-type, suggesting a role in regulating macrophage contribution to inflammation in obesity.
The Slc37A2 protein is post-translationally modified with N-linked glycans and migrates as a heterogeneous species of 50–75 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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