Thermo Fisher Scientific GZF1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GZF1. Recombinant protein control fragment (Product #RP-93594). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GZF1,uniProtId:Q9H116-1,ncbiNodeId:9606,antigenRange:109-200,antigenLength:711,antigenImageFileName:PA5-55099_GZF1_Q9H116-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55099_GZF1_Q9H116-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642285

Product Specific Information

Immunogen sequence: MLEVAEKLKC LDLSETCFQL KKQMLESVLL ELQNFSESQE VEVSSGSQVS AAPAPRASVA TDGPHPSGLT DSLDYPGERA SNGMSSDLPP KK

Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 73%.

Target Information

The GDNF-inducible zinc finger protein 1 (GZF1) is a sequence-specific transcriptional repressor with a BTB/POZ domain and ten zinc finger motifs whose expression is required for renal branching morphogenesis during kidney development. GZF1 binds to the 5`regulatory region of the homeodomain protein HOXA10, suggesting that GZF1 may play a role in morphogenesis other than kidney development. Recent experiments have indicated that GZF1 associates with nucleolin and this association is mediated by the first four zinc finger motifs of GZF1. It is thought that Nucleolin modulates the subcellular localization of GZF1 as well as its transcriptional repressor activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.