Thermo Fisher Scientific CACNG3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CACNG3 (Calcium Channel gamma-3). Validated for Western Blot. Recognizes human and mouse samples. Supplied as liquid, 0.8 mg/mL, affinity purified. For research use only.
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Applications
- Western Blot (WB): 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full-length fusion protein of human Calcium Channel gamma-3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2692084 |
Product Specific Information
Predicted to react with human samples.
Target Information
Calcium Channel gamma-3 is a member of voltage-dependent calcium channels (VDCCs) that allow neurons to tailor calcium signaling to discrete cellular regions. N-Type VDCCs exist before birth, consistent with a role in neuronal migration, while most subunit expression occurs postnatally and contributes to synaptic transmission in hippocampal fields.
Calcium Channel gamma-3 functions as a type I transmembrane AMPA receptor regulatory protein (TARP) that modulates both trafficking and channel gating of AMPA receptors. It belongs to an eight-member subfamily of the PMP-22/EMP/MP20 family. Dysfunction of the CACNG3 gene is associated with susceptibility to childhood absence epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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