Thermo Fisher Scientific FMO1 Polyclonal Antibody
Thermo Fisher FMO1 Polyclonal Antibody는 Rat에 반응하며 Rabbit IgG 기반의 액상 항체입니다. Western blot에 최적화되어 있으며, FMO1 중간 영역(aa 40-89) 펩타이드로 면역화되었습니다. 고순도 친화 크로마토그래피 정제, 0.5 mg/mL 농도, -20°C 보관 조건.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human FMO1 (aa 40–89) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691333 |
Product Specific Information
This target displays homology in the following species:
Cow: 100% | Dog: 100% | Guinea Pig: 93% | Horse: 100% | Human: 100% | Mouse: 100% | Pig: 100% | Rabbit: 100% | Rat: 100%
Target Information
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in humans, resulting in a small subpopulation with reduced TMA N-oxidation capacity, known as fish odor syndrome (Trimethylaminuria).
Three forms of the enzyme are encoded by genes clustered in the 1q23–q25 region:
- FMO1: Found in fetal liver
- FMO2: Found in adult liver
- FMO3: Associated with Trimethylaminuria
Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyze oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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