Thermo Fisher Scientific ERCC1 Monoclonal Antibody (8F1)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

View 4 publications 4 publications

Immunohistochemistry (IHC)

-

View 59 publications 59 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

-

View 1 publication 1 publication

Flow Cytometry (Flow)

0.5-1 µg/test

-

Immunoprecipitation (IP)

Assay-dependent

View 3 publications 3 publications

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Published species

Hamster, Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

8F1

Immunogen

Recombinant full length human ERCC1 protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10987315

Product Specific Information

MA5-13912 targets ERCC1 in IP, IHC (P), FACS and WB applications and shows reactivity with human, mouse and rat samples.

The MA5-13912 immunogen is recombinant full length human ERCC1 protein.

Target Information

ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5`-incision during DNA repair. It is responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). It participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. (Uniprot)

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.