Thermo Fisher Scientific CD4 Monoclonal Antibody (GK1.5), FITC
마우스 CD4 단백질을 인식하는 단클론 항체로, FITC로 표지되어 유세포분석(Flow Cytometry)에 적합합니다. Rat IgG2b 아이소타입이며, 액상 형태로 제공됩니다. PBS(pH 7.4) 용액에 보관하며, 4°C 암소 보관이 권장됩니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–2 µg/mL
- Publications: View 3 publications
Miscellaneous PubMed (Misc)
- Publications: View 4 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published species | Mouse |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GK1.5 |
| Immunogen | Mouse CTL clone V4 cells |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157830 |
Additional Formats
Product Specific Information
This antibody reacts with an extracellular epitope of mouse CD4 transmembrane glycoprotein (55 kDa).
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed on T helper cells but can also be found on monocytes, macrophages, and dendritic cells. Tissue-level expression includes thymus, lymph nodes, tonsils, spleen, and specific regions of the brain and gut. CD4 facilitates early T-cell activation through association with the T-cell receptor complex and Lck kinase, and may play a role in neuronal damage in immune-mediated diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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