Thermo Fisher Scientific RNF41 Polyclonal Antibody
RNF41 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC(P) 및 ICC/IF에 사용 가능하며, 인간 RNF41 재조합 단백질을 면역원으로 제작. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공.
- 카탈로그번호
- PA553495
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RNF41. Recombinant protein control fragment (Product #RP-91674). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C (short term). For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646679 |
Product Specific Information
Immunogen sequence:
DAVLQAVIKR SLVESGCPAS IVNELIENAH ERSWPQGLAT LETRQMNRRY YENYVAKRIP GKQAVVVMAC ENQHMGDDMV QEPGLVMIFA HGVEEI
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain able to bind two zinc atoms. Proteins with this domain are generally involved in the ubiquitination pathway of protein degradation.
Nrdp1, also known as RNF41 (RING finger protein 41), SBBI03, or FLRF, is a 317 amino acid protein containing one RING-type zinc finger and one SIAH-type zinc finger. It is expressed in testis, ovary, and prostate, and functions as an E3 ubiquitin-protein ligase that transfers ubiquitin from an E2 enzyme to degradation-targeted substrates. Specifically, Nrdp1 interacts with ErbB-3 and UBPY, targeting them for proteasomal degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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