Thermo Fisher Scientific CDK8 Polyclonal Antibody
CDK8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot 및 Immunocytochemistry에 적합하며, 인간 CDK8에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
- 카탈로그번호
- PA565388
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific CDK8 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CDK8 (Recombinant protein control fragment, Product #RP-104796) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2662899 |
Product Specific Information
Immunogen sequence:
LTEEEPDDKGD KKNQQQQQGN NHTNGTGHPG NQDSSHTQGP PLKKVRVVPP TTTSGGLIMT SDYQRSNPHA AYPNPGPSTS QPQSSMGYSA TS
Highest antigen sequence identity to the following orthologs:
- Mouse: 96%
- Rat: 33%
Target Information
CDK8 phosphorylates the carboxy-terminal domain of the largest subunit of RNA polymerase II and is coexpressed and copurified with Cyclin C. CDK8 belongs to a family of cyclin-dependent kinases (cdks) that regulate cell cycle progression. Members such as Cdk2, Cdk4, and Cdk6 play roles in different phases of the cell cycle. Human Cdk8–Cyclin C complex may interact with RNA polymerase, influencing transcription mechanisms related to cell division.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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