Thermo Fisher Scientific GM2A Polyclonal Antibody
인간 GM2A 단백질을 인식하는 토끼 폴리클로날 항체. IHC(P)에서 10–12.5 µg/mL로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제형이며, 단기 4°C 보관 및 장기 -20°C 보관 권장. 연구용으로만 사용.
- 카탈로그번호
- PA532784
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 10–12.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 14 amino acid peptide from N-terminus of human GM2A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550246 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon (100%)
Monkey (86%)
Target Information
This gene encodes a small glycolipid transport protein which acts as a substrate-specific co-factor for the lysosomal enzyme beta-hexosaminidase A.
Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of ganglioside GM2 and other molecules containing terminal N-acetyl hexosamines.
Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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