Thermo Fisher Scientific TYRO3 Monoclonal Antibody (1C10E8, 9A3F2)
TYRO3 단백질을 검출하기 위한 Mouse IgG1 단일클론 항체로, Human 시료에 반응합니다. Western blot, ICC/IF, ELISA 등 다양한 응용에 적합합니다. 비결합형 액상 형태이며, 장기 보관 시 -20°C에서 보관합니다.
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Thermo Fisher Scientific TYRO3 Monoclonal Antibody (1C10E8, 9A3F2)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C10E8, 9A3F2 |
| Immunogen | Purified recombinant fragment of TYRO3 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10980105 |
Product Specific Information
MA5-15340 targets TYRO3 in indirect ELISA, ICC, IF, and WB applications and shows reactivity with Human samples.
The MA5-15340 immunogen is a purified recombinant fragment of TYRO3 expressed in E. coli.
Target Information
TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6.
It regulates many physiological processes including cell survival, migration, and differentiation.
Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain, providing docking sites for downstream signaling molecules.
Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, signal transduction, cell adhesion, and cytoskeleton reorganization.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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