Thermo Fisher Scientific P2X6 Polyclonal Antibody
P2X6 수용체를 인식하는 Rabbit Polyclonal Antibody로 WB, IHC, ICC/IF에 사용 가능. ATP-개폐 이온 채널 연구에 적합하며, 동결건조 형태로 제공되어 -20°C 보관. 재구성 시 50 µL 탈이온수 사용.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (IHC) | Assay-Dependent |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)RTKYEEARAPKATTNSA, corresponding to amino acid residues 363–379 of rat P2X6 Receptor |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.7 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736299 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
P2rx6 encodes receptors that are members of the ligand-gated ion channel family that open in response to extracellular ATP.
Each P2rx6 receptor is composed of a trimer of subunits (P2X1–7), all sharing a common structure of two transmembrane domains.
The protein encoded by the P2rx6 gene belongs to the family of P2X receptors, which are ATP-gated ion channels mediating rapid and selective permeability to cations.
P2rx6 is predominantly expressed in skeletal muscle and regulated by p53. The encoded protein associates with VE-cadherin at adherens junctions of human umbilical vein endothelial cells.
Alternative splicing results in multiple transcript variants of P2rx6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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