Thermo Fisher Scientific U2AF1L4 Monoclonal Antibody (OTI8B1), TrueMAB
U2AF1L4 단백질을 인식하는 Mouse monoclonal 항체로, Western blot에 최적화됨. Human 시료에 반응하며, 고순도 Affinity chromatography로 정제됨. 안정한 PBS/BSA/glycerol buffer에 보관되며, 연구용으로만 사용 가능.
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- TA810435
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- pk
카탈로그
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8B1 |
| Immunogen | Full length human recombinant protein of human U2AF1L4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
RNA-binding protein that functions as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein and protein-RNA interactions required for accurate 3′-splice site selection. Enhances U2AF2 binding to weak pyrimidine tracts and participates in regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. Binds RNA at the AG dinucleotide at the 3′-splice site, showing preference for AGC or AGA. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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