Thermo Fisher Scientific FZD4 Polyclonal Antibody
Human FZD4 단백질을 인식하는 Goat 유래 Polyclonal Antibody로 Western Blot에 적합. 합성 펩타이드 면역원 사용, 0.5 mg/mL 농도 액상 형태. Rat에서도 반응 예측되며, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DEEERRCDPIRIS) corresponding to the internal amino acids of FZD4 (aa 39–52). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10978890 |
Product Specific Information
- This antibody is predicted to react with rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 16,000.
Target Information
FZD4 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway.
A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. Frizzled 4 is widely expressed, particularly in heart, skeletal muscle, ovary, and fetal kidney. Transcripts have also been identified in liver, kidney, pancreas, spleen, and fetal lung, and in smaller amounts in placenta, adult lung, prostate, testis, colon, and fetal brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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