Thermo Fisher Scientific RAB23 Monoclonal Antibody (OTI4C7)
RAB23 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 IHC(P)에서 검증됨. Human 시료에 반응하며, 1 mg/mL 농도의 액상 형태. PBS buffer(1% BSA, 50% glycerol)로 안정화되어 있으며 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–234 of RAB23 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725170 |
Target Information
The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec, and Rho/Rab subfamilies. Rab proteins play key roles in endocytosis and biosynthetic protein transport, facilitating the movement of carrier vesicles from the endoplasmic reticulum to the Golgi complex and secretory vesicles.
Rab 23 (also known as HSPC137) is a 237 amino acid member of the Rab family, localized to the cytoplasmic side of the cell membrane. It is implicated in intracellular protein transport and signal transduction mediated by small GTPases.
Mutations in the RAB23 gene are associated with Carpenter syndrome (ACPS2), characterized by obesity, cardiac defects, polysyndactyly, and craniosynostosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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