Thermo Fisher Scientific SLC39A5 Monoclonal Antibody (OTI2F2)
인간 SLC39A5 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, WB 및 IHC(P) 응용에 적합합니다. 고순도 친화 크로마토그래피 정제 제품이며, 안정적인 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 48–178 of SLC39A5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725365 |
Target Information
The zinc transporter ZIP5 (SLC39A5) is a member of the family of divalent ion transporters. Zinc is essential for cellular growth, development, and differentiation. ZIP5 is closely related to ZIP4 and is found in tissues such as intestine, pancreas, liver, and kidney. Unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and is not downregulated by zinc repletion. Evidence suggests reciprocal regulation between ZIP4 and ZIP5, where ZIP5 mRNA translation decreases and ZIP5 protein is rapidly internalized and degraded under zinc deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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