Thermo Fisher Scientific HBS1L Polyclonal Antibody

Thermo Fisher Scientific HBS1L Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, A431, HeLa, HepG2
• Predicted reactivity: Bovine (87%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues, with the highest expression in heart and skeletal muscle.
The intergenic region between this gene and the MYB gene is a quantitative trait locus (QTL) controlling fetal hemoglobin level, influencing erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content.
DNA polymorphisms at this region are associated with fetal hemoglobin levels and pain crises in sickle cell disease.
A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E.
Multiple alternatively spliced transcript variants encoding different protein isoforms have been identified.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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