Thermo Fisher Scientific DAB2 Monoclonal Antibody (2H7C4)
DAB2 단백질을 인식하는 Mouse monoclonal antibody (Clone 2H7C4). Western blot, ICC/IF, Flow cytometry, ELISA에 사용 가능. Human 시료 반응성. Protein G 정제, 1 mg/mL 농도. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution Range |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2H7C4 |
| Immunogen | Purified recombinant fragment of human DOC2 (AA: 652–749) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787347 |
Product Specific Information
MA5-31723 has been tested in indirect ELISA.
Target Information
DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein shares 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein. Homology is strongest in the N-terminal region corresponding to the phosphotyrosine interaction domain. Down-regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (Differentially expressed in Ovarian Cancer) and is distinct from DOC2A and DOC2B (double C2-like domains, alpha and beta).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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