Thermo Fisher Scientific CD20 Polyclonal Antibody
CD20 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, Flow Cytometry, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat에 반응하며, Protein A로 정제된 고품질 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human CD20 (amino acids 133–182) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD20 is a non-glycosylated surface phosphoprotein with a molecular weight of 33–37 kDa, depending on phosphorylation status. It is expressed on mature and most malignant B cells, as well as a subpopulation of T lymphocytes and follicular dendritic cells. CD20 is involved in regulating calcium conductance, cell cycle progression, and B-cell proliferation. It remains on the cell surface after antibody binding, making it a valuable target for therapeutic B-cell depletion. CD20 dysfunction is associated with Ms4a1-related common variable immune deficiency.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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