Thermo Fisher Scientific MAPK13 Polyclonal Antibody
MAPK13 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체로, Western blot, IHC, ELISA, IP 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성이 있으며, Chicken IgY로 제작되었습니다. Affinity chromatography로 정제된 액상 항체로 연구용에 적합합니다.
- 카탈로그번호
- MAPK13-101Y
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 310–360 on human Mitogen-activated protein kinase 13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase that transduces extracellular signals such as cytokine and environmental stress responses. It regulates keratinocyte differentiation and is activated by environmental stresses and proinflammatory cytokines. Activation requires phosphorylation by MAP kinase kinases or autophosphorylation via interaction with MAP3K7IP1/TAB1. Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, suggesting roles in transcription, cell cycle regulation, and genotoxic stress response. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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