Thermo Fisher Scientific CHRNA7 Monoclonal Antibody (7F10F1)
CHRNA7 단백질을 인식하는 마우스 단클론 항체로 Western blot, Flow cytometry, ELISA에 사용 가능. 인간 및 랫트 반응성. Protein G로 정제된 1 mg/mL 액상 형태. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7F10F1 |
| Immunogen | Purified recombinant fragment of human CHRNA7 (AA: extra 52–259) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787314 |
Product Specific Information
MA5-31690 has been tested in indirect ELISA.
Target Information
Chromosome 15 encodes over 700 genes and comprises nearly 3% of the human genome. CHRFAM7A, a fusion protein comprised of FAM7A and AChR alpha7, is encoded by the CHRFAM7A gene, which is located on a region of human chromosome 15 associated with several neuropsychiatric disorders such as schizophrenia and bipolar affective disorder.
CHRFAM7A (also known as D-10 or CHRNA7) is a 412 amino acid multi-pass membrane protein belonging to the nicotinic acetylcholine receptor (nAChR) subfamily of ligand-gated ion channel proteins, which mediate signal transmission at synapses. CHRFAM7A is expressed in the hippocampus, and alternative splicing of the CHRFAM7A gene produces two splice variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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