Thermo Fisher Scientific PDE5 Polyclonal Antibody
Thermo Fisher Scientific의 PDE5 Polyclonal Antibody는 인간 PDE5 단백질을 인식하는 토끼 유래 다클론 항체입니다. IHC(P) 및 ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS(glycerol 포함) 용액 형태로 제공되며, 연구용으로만 사용 가능합니다.
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- PA552093
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PDE5. Recombinant protein control fragment (Product # RP-102419) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645329 |
Product Specific Information
Immunogen sequence:
FAAYLAFCGI VLHNAQLYET SLLENKRNQV LLDLASLIFE EQQSLEVILK KIAATIISFM QVQKCTIFIV DEDCSDSFSS VFHMECEELE KSSDTLTREH DANKINYMYA QYVKNTMEPL NIPDVSKDKR FPWTTENTGN
Highest antigen sequence identity to the following orthologs:
- Mouse: 92%
- Rat: 91%
Target Information
The cyclic monophosphate nucleotides (cyclic adenosine monophosphate [cAMP] and cyclic guanosine monophosphate [cGMP]) are found ubiquitously in mammalian cells and act as second messenger transducers to effect the intracellular actions of a variety of G protein coupled receptors (GPCRs) for hormones, cytokines, and neurotransmitters.
Cyclic nucleotides are important intracellular second messengers that play a critical role in various signal transduction processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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