Thermo Fisher Scientific CYP4X1 Polyclonal Antibody

Thermo Fisher Scientific CYP4X1 Polyclonal Antibody

Applications

• Western Blot (WB)

Tested Dilution: 1.0 µg/mL

Product Specifications

Product Specific Information

This target displays homology in the following species:

• Dog: 100%
• Guinea Pig: 86%
• Horse: 100%
• Human: 100%
• Mouse: 86%
• Rabbit: 79%
• Rat: 86%

Target Information

Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs.
The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson’s, Gaucher disease and Usher syndrome are also associated with chromosome 1.
A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
The CYP4X1 gene product has been provisionally designated CYP4X1 pending further characterization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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