Thermo Fisher Scientific TSC22D3 Monoclonal Antibody (OTI3F3), TrueMAB
Human TSC22D3 단백질을 인식하는 Mouse IgG2b 단클론 항체로, Western blot 및 Immunocytochemistry에 적합합니다. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다. 항염증 및 면역억제 관련 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F3 |
| Immunogen | Full length human recombinant protein of human TSC22D3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TSC22 domain family member 3 (TSC22D3) is a leucine zipper protein functioning as a transcriptional regulator. Its expression is stimulated by glucocorticoids and IL-10, playing a key role in anti-inflammatory and immunosuppressive mechanisms.
TSC22D3 interacts with NF-Kappa-B and AP-1, inhibiting their activities, and acts as a transcriptional co-activator for nuclear receptors and NF-Kappa-B. It is also involved in mesenchymal stem cell differentiation toward osteoblasts and bone formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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