Thermo Fisher Scientific UBXD2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human UBXD2. Recombinant protein control fragment (Product #RP-96121). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:UBXD2,uniProtId:Q92575-1,ncbiNodeId:9606,antigenRange:315-404,antigenLength:508,antigenImageFileName:PA5-57611_UBXD2_Q92575-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57611_UBXD2_Q92575-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649212

Product Specific Information

Immunogen sequence: ERSTVARIQF RLPDGSSFTN QFPSDAPLEE ARQFAAQTVG NTYGNFSLAT MFPRREFTKE DYKKKLLDLE LAPSASVVLL PAGRPTASIV

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 93%.

Target Information

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. MAFA cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its ocogenic activity. Serves as an ocogene or tumor supressor depending on the cell context.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.