Thermo Fisher Scientific UBXD2 Polyclonal Antibody
Thermo Fisher Scientific UBXD2 폴리클로날 항체는 Human, Mouse, Rat 시료에 반응하며 Western blot, IHC, ICC/IF 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공되며, 안정적인 저장 및 높은 특이성을 제공합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human UBXD2. Recombinant protein control fragment (Product #RP-96121). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649212 |
Product Specific Information
Immunogen sequence:
ERSTVARIQF RLPDGSSFTN QFPSDAPLEE ARQFAAQTVG NTYGNFSLAT MFPRREFTKE DYKKKLLDLE LAPSASVVLL PAGRPTASIVHighest antigen sequence identity to orthologs:
- Mouse: 92%
- Rat: 93%
Target Information
MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element regulating pancreatic beta cell-specific expression of the insulin gene. MAFA cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. It can act as an oncogene or tumor suppressor depending on the cellular context.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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