Thermo Fisher Scientific ASCC1 Polyclonal Antibody
Human ASCC1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC(P) 검증 완료. 고순도 항원 친화 크로마토그래피 정제, PBS/glycerol buffer에 보존. 연구용으로만 사용.
- 카탈로그번호
- PA558221
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ASCC1 (Product #RP-97091) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2638279 |
Product Specific Information
Immunogen sequence:
YAKVHMKDGS NRLQELVDRV LERFQASGLI VKEWNSVKLH ATVMNTLFRK DPNAEGRYNL YTAEGKYIFK ERESFDGRN
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 91%
Target Information
The ASCC1 gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex, a transcriptional coactivator involved in gene transactivation by multiple transcription factors such as AP-1, NF-κB, and SRF.
The encoded protein contains an N-terminal KH-type RNA-binding motif required for AP-1 transactivation.
Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma.
Alternatively spliced transcripts encoding multiple isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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