Thermo Fisher Scientific BLNK Polyclonal Antibody
BLNK 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot, ICC/IF, Flow cytometry에 사용 가능. 인간 반응성, 다양한 종에서 예측 반응. 고순도 액상 형태로 안정적 보관 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C terminus amino acids KDSTRLKYAVKVS (aa 444–456) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2228018 |
Product Specific Information
- Predicted to react with bovine, canine, mouse, porcine, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
B cell linker protein (BLNK) is encoded by the BLNK gene located on chromosome 10 in humans. Also known as SLP-65 (Src homology 2 domain-containing leukocyte protein of 65 kDa).
BLNK acts as an adaptor protein in the B cell receptor signaling cascade. Deficiency in BLNK leads to improper B cell development.
BLNK is phosphorylated by Syk kinase, providing a platform for interaction with signaling intermediaries such as Vav GEF and Grb2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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